| 1 | | ZY5P-HAH1 |
|
1A
|
Catalytic Mechanism of Nonglycosidic C?N Bond Formation by the Pseudoglycosyltransferase Enzyme VldE
|
Takeshi Tsunoda
|
英語 / English
|
ACS Catalysis
|
2023
|
13
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13369
|
| 2 | | 9429-Y7E6 |
|
1A
|
Structural insights into the substrate specificity and activity of a novel mannose 2-epimerase from Runella slithyformis
|
Wang, Hang
|
英語 / English
|
Acta Crystallographica Section D
|
2023
|
79
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585
|
| 3 | | GBAC-79AC |
2022G044
|
1A/1A
|
Structure-Function Analysis of the S-Glycosylation Reaction in the Biosynthesis of Lincosamide Antibiotics
|
阿部 郁朗/Ikuro ABE; 森貴裕
|
英語 / English
|
Angewandte Chemie-International Edition
|
2023
|
62
|
|
| 4 | | TJ3Y-BVAC |
2019G535; 2021G507; 2018G048
|
1A/1A; 1A/1A; 1A/1A
|
Assessment of inconsistencies in the solvent-accessible surfaces of proteins between crystal structures and solution structures observed by LC-MS.
|
松井 崇/Takashi MATSUI; Eiji KOJITANI; Taichi TAKASAWA; Arisa SUTO; Ami TAMARI; Go WATANABE; Yoshio KODERA
|
英語 / English
|
Biochemical and Biophysical Research Communications
|
2023
|
640
|
97
|
| 5 | | D4PS-5R15 |
2020G524; 2020RP-23
|
NE3A; 1A/1A
|
Substrate Recognition Mechanism of a Trichostatin A‐Forming Hydroxyamidotransferase
|
永田 隆平/Ryuhei NAGATA; 西山真; 葛山 智久/Tomohisa KUZUYAMA
|
英語 / English
|
Biochemistry
|
2023
|
62
|
1833
|
| 6 | | Z20T-JES2 |
2012G001, 2013R-11
|
1A
|
Identification of the Acidification Mechanism of the Optimal pH for RNase He1
|
Takebe, Katsuki
|
英語 / English
|
Biological & Pharmaceutical Bulletin
|
2023
|
46
|
1778
|
| 7 | | N2R5-KAEA |
2021G011; 2019G016
|
1A/1A; 17A/17A; 17A/17A
|
Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis
|
Mineyuki Mizuguchi
|
英語 / English
|
Bioorganic & Medicinal Chemistry
|
2023
|
90
|
|
| 8 | | WWC5-0X57 |
2020G521
|
1A/1A
|
Structural basis for the substrate specificity switching of lysoplasmalogen-specific phospholipase D from Thermocrispum sp. RD004668
|
濱名 宏章; 安武 義晃/Yoshiaki YASUTAKE; 村山(加藤)美幸; 保坂 俊彰; 白水 美香子; 酒瀬川信一; 杉森 大助; 村山 和隆
|
英語 / English
|
Bioscience Biotechnology and Biochemistry
|
2023
|
87
|
74
|
| 9 | | 5MMB-VSXR |
2021G519; 2019G508; 2017G513
|
5A/ 5A; NE3A/NE3A; 1A/1A; 5A/ 5A; NE3A/NE3A; 17A/17A
|
Characterization and alteration of product specificity of Beijerinckia indica subsp. indica β-fructosyltransferase
|
LI DING/DING LI; 宮坂 祐希/Yuki MIYASAKA; 窪田 有紗/Arisa KUBOTA; 西河 淳/Atsushi NISHIKAWA; 殿塚 隆史/Takashi TONOZUKA
|
英語 / English
|
Bioscience Biotechnology and Biochemistry
|
2023
|
87
|
981
|
| 10 | | J487-A9M2 |
2021Y005
|
1A/1A
|
A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1
|
沼田 和志 / Masashi Numata; 萩野谷 憲康 / Noriyasu Haginoya
|
英語 / English
|
Cancer Cell International
|
2023
|
23
|
|
| 11 | | 4RCT-4C6C |
2021G054
|
1A/1A; 17A/17A
|
Functional molecular evolution of a GTP sensing kinase: PI5P4Kβ.
|
竹内 恒/Koh TAKEUCHI; Miki Senda; Atsuo Sasaki; Toshiya Senda
|
英語 / English
|
FEBS Journal
|
2023
|
290
|
4419
|
| 12 | | ERVW-G632 |
|
1A
|
Structural insights into recognition of SL4, the UUCG stem-loop, of human U1 snRNA by the ubiquitin-like domain, including the C-terminal tail in the SF3A1 subunit of U2 snRNP
|
Nobukazu Nameki
|
英語 / English
|
Journal of Biochemistry
|
2023
|
174
|
203
|
| 13 | | X2CX-KMZD |
2015Y007
|
1A/1A
|
Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor
|
Ryutaro Kanada
|
英語 / English
|
Journal of Medicinal Chemistry
|
2023
|
66
|
695
|
| 14 | | CBX2-W7FT |
|
1A
|
Jungfraujoch: hardware-accelerated data-acquisition system for kilohertz pixel-array X-ray detectors
|
Leonarski, Filip
|
英語 / English
|
Journal of Synchrotron Radiation
|
2023
|
30
|
227
|
| 15 | | U0X3-CUAJ |
2019Y005
|
1A/1A
|
Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma.
|
岸川 秀平/Shuhei KISHIKAWA
|
英語 / English
|
Molecular Cancer Therapeutics
|
2023
|
22
|
317
|
| 16 | | Y00S-2DEC |
|
1A
|
Molecular basis for carrier protein-dependent amide bond formation in the biosynthesis of lincosamide antibiotics
|
Takahiro Mori
|
英語 / English
|
Nature Catalysis
|
2023
|
6
|
531
|
| 17 | | 4GJK-DDSP |
2016G083; 2017G089; 2019G018; 2020RP-04
|
1A/1A; 17A/17A; NE3A/NE3A; NW12A/NW12A; 1A/1A; NE3A/NE3A; NW12A/NW12A; 5A/ 5A; NE3A/NE3A; NW12A/NW12A; 1A/1A
|
A bacterial sulfoglycosidase highlights mucin O-glycan breakdown in the gut ecosystem
|
Toshihiko KATO; 山田 千早/Chihaya YAMADA; ブランパン 騰真/Toma BLANPAIN; 伏信 進矢/Shinya FUSHINOBU; Takane KATAYAMA
|
英語 / English
|
Nature Chemical Biology
|
2023
|
19
|
778
|
| 18 | | J9FH-DCNE |
2019G163
|
1A
|
Co-evolution-based prediction of metal-binding sites in proteomes by machine learning
|
Cheng Y.
|
英語 / English
|
Nature Chemical Biology
|
2023
|
19
|
548
|
| 19 | | 60HW-DUT6 |
2017R-37
|
1A
|
Design of allosteric sites into rotary motor V$_1$-ATPase by restoring lost function of pseudo-active sites
|
Takahiro Kosugi
|
英語 / English
|
Nature Chemistry
|
2023
|
15
|
1591
|
| 20 | | H1G2-JP84 |
|
1A
|
A blocking monoclonal antibody reveals dimerization of intracellular domains of ALK2 associated with genetic disorders
|
Katagiri, Takenobu
|
英語 / English
|
Nature Communications
|
2023
|
14
|
|
| 21 | | R6NJ-W179 |
2020G538
|
1A/1A
|
Structure of lasso peptide epimerase MslH reveals metal-dependent acid/base catalytic mechanism
|
Nakashima Y. ; Kawakami A
|
英語 / English
|
Nature Communications
|
2023
|
14
|
|
| 22 | | CKUH-Z69C |
2015G020, 2014R-40, 2015R-36; 2016G083; 2016R-69; 2017G088; 2017G089; 2019G017; 2019G018; 2021G052; 2022G034; 2021PF-B026; 2022PF-B011; 2022PF-B014; 2023G052
|
17A/17A; NE3A/NE3A; NW12A/NW12A; 1A/1A; 5A/ 5A; NW12A/NW12A; 1A/1A; 17A/17A; 5A/ 5A; NE3A/NE3A; NW12A/NW12A; 1A/1A; NE3A/NE3A; NW12A/NW12A; 1A/1A; 5A/ 5A; NE3A/NE3A; NW12A/NW12A; 5A/ 5A; NE3A/NE3A; NW12A/NW12A; 1A/1A; 5A/ 5A; 17A/17A; NW12A/NW12A; 1A/1A; 5A/ 5A; 17A/17A; NE3A/NE3A; NW12A/NW12A; 15A2/15A2; 10C/10C; 10C/10C; NE3A/NE3A
|
Identification and characterization of endo-α-, exo-α-, and exo-β-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria
|
ブランパン 騰真/Toma BLANPAIN; 伏信 進矢/Shinya FUSHINOBU; 荒川 孝俊/Takatoshi ARAKAWA; 中島 千穂/Chiho NAKASHIMA; 赤井 元気/Genki AKAI; 清水 伸隆 /Nobutaka SHIMIZU; 福島 陸/Riku FUKUSHIMA; 山田 千早/Chihaya YAMADA
|
英語 / English
|
Nature Communications
|
2023
|
14
|
|
| 23 | | X48Y-T463 |
2019G163
|
1A
|
DNA?TCP complex structures reveal a unique recognition mechanism for TCP transcription factor families
|
Zhang Y.
|
英語 / English
|
Nucleic Acids Research
|
2023
|
51
|
434
|
| 24 | | PWE3-DM8D |
|
1A
|
Structure of the Caenorhabditis elegans m6A methyltransferase METT10 that regulates SAM homeostasis
|
Ju, Jue
|
英語 / English
|
Nucleic Acids Research
|
2023
|
51
|
2434
|
| 25 | | ZPXW-B44B |
2016G617; 2016G606; 2018G636; 2018G634; 2020G658
|
NW12A/NW12A; 5A/ 5A; 1A/1A; 10C/10C; 5A/ 5A; 17A/17A; 10C/10C; 5A/ 5A; 17A/17A; NW12A/NW12A
|
Crystal structure and activity of a de novo enzyme, ferric enterobactin esterase Syn-F4 / 新規人工酵素Syn-F4鉄エンテロバクチンエステラーゼの結晶構造と活性
|
栗原 航大/Kodai KURIHARA; 梅澤 公二; Ann E. Donnelly; Brendan Sperling; Guanyu Liao; Michael H. Hecht; 新井 亮一/Ryoichi ARAI
|
英語 / English
|
Proceedings of the National Academy of Sciences of the United States of America
|
2023
|
120
|
|
| 26 | | MR0B-4S6E |
|
1A
|
Structural and molecular insight into antibody recognition of dynamic neoepitopes in membrane tethered MUC1 of pancreatic cancer cells and secreted exosomes
|
Hajime Wakui
|
英語 / English
|
RSC Chemical Biology
|
2023
|
4
|
564
|
| 27 | | 7J04-0AJ3 |
|
1A, 17A
|
Structural bases for the Charcot-Marie-Tooth disease induced by single amino acid substitutions of myelin protein zero
|
Sakakura M.
|
英語 / English
|
Structure
|
2023
|
31
|
1452
|
| 28 | | JRA8-W34W |
2016R-46
|
1A/1A
|
Chloride ions evoke taste sensations by binding to the extracellular ligand-binding domain of sweet/umami taste receptors
|
渥美 菜奈子/Nanako ATSUMI; 山下 敦子/Atsuko YAMASHITA
|
英語 / English
|
eLife
|
2023
|
12
|
|
| 29 | | 2NM3-63VT |
|
17A, 1A
|
Structural basis of EHEP-mediated offense against phlorotannin-induced defense from brown algae to protect akuBGL activity
|
Xiaomei Sun
|
英語 / English
|
eLife
|
2023
|
88939.3
|
|
| 30 | | BSAW-J03F |
|
1A
|
Efficient production of bispecific antibody by FAST-IgTM and its application to NXT007 for the treatment of hemophilia A
|
Koga, Hikaru
|
英語 / English
|
mAbs
|
2023
|
15
|
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