| 1 | | SUBC-AWNS |
2012G132
|
17A/17A
|
Revealing a Hidden Intermediate of Rotatory Catalysis with X-ray Crystallography and Molecular Simulations
|
Mrinal Shekhar; Chitrak Gupta; 鈴木 花野/Kano SUZUKI
|
英語 / English
|
ACS Central Science
|
2022
|
27
|
915
|
| 2 | | MRKF-CF2K |
|
17A
|
Ligand Recognition by the Lipid Transfer Domain of Human OSBP Is Important for Enterovirus Replication
|
Jun Kobayashi
|
英語 / English
|
ACS Infectious Diseases
|
2022
|
8
|
1161
|
| 3 | | 0ZBA-UPV4 |
2017G554; 2019G592
|
17A/17A; 17A/17A
|
Effects of Myristate on the Induced Circular Dichroism Spectra of Aripiprazole Bound to Human Serum Albumin: A Structural?Chemical Investigation
|
Kenshiro Hirata; 河合 聡人/Akito KAWAI
|
英語 / English
|
ACS Omega
|
2022
|
7
|
4413
|
| 4 | | ZMYE-96A6 |
2017G554; 2019G592
|
17A/17A; 17A/17A
|
Chlorine Atoms of an Aripiprazole Molecule Control the Geometry and Motion of Aripiprazole and Deschloro-aripiprazole in Subdomain IIIA of Human Serum Albumin
|
河合 聡人/Akito KAWAI
|
英語 / English
|
ACS Omega
|
2022
|
7
|
29944
|
| 5 | | 23HA-F73D |
2019G159
|
17A/17A
|
Structural and functional identification of uncharacterized metallo-β-lactamase superfamily protein TW9814 as a phosphodiesterase with unique metal coordination
|
PARK Soo-Bong/Soo-Bong PARK; JEONG Bo-Gyeong/Bo-Gyeong JEONG; CHA Sunshin/Sunshin CHA
|
英語 / English
|
Acta Crystallographica Section D
|
2022
|
D78
|
532
|
| 6 | | SGBS-R7X4 |
2019G051
|
17A
|
Synthesis of a Negatively Curved Nanocarbon Molecule with an Octagonal Omphalos via Design-of-Experiments Optimizations Supplemented by Machine Learning
|
Koki Ikemoto; Misato Akiyoshi; Tatsuru Mio; Kaito Nishioka; Sota Sato; Hiroyuki Isobe
|
英語 / English
|
Angewandte Chemie-International Edition
|
2022
|
61
|
e202204035
|
| 7 | | 6P9X-M7UE |
2020G504
|
17A
|
A Defective Nanotube Molecule of C552H496N24 with Pyridinic and Pyrrolic Nitrogen Atoms
|
Koki Ikemoto
|
英語 / English
|
Angewandte Chemie-International Edition
|
2022
|
61
|
|
| 8 | | 33AT-RXKS |
2019G146
|
17A
|
Crystal structure of the adenylation domain from an ε-poly-L-lysine synthetase provides molecular mechanism for substrate specificity
|
Okamoto T.
|
英語 / English
|
Biochemical and Biophysical Research Communications
|
2022
|
596
|
43
|
| 9 | | AB45-7R5X |
2018G523; 2020G531; 2022G595
|
17A/17A; 17A/17A; 17A/17A
|
Structural and mutational studies suggest key residues to determine whether stomatin SPFH domains form dimers or trimers
|
小松 友哉/Tomoya KOMATSU; 横山 英志/Hideshi YOKOYAMA
|
英語 / English
|
Biochemistry and Biophysics Reports
|
2022
|
32
|
|
| 10 | | ZH0J-YW9Y |
2019G595
|
17A
|
Lithocholic Acid Amides as Potent Vitamin D Receptor Agonists
|
Yoshihara A.
|
英語 / English
|
Biomolecules
|
2022
|
12
|
|
| 11 | | B523-UPR7 |
2015G019; 2015G020; 2016R-69; 2017G089; 2019G018; 2021PF-B026
|
5A/ 5A; NE3A/NE3A; NW12A/NW12A; 17A/17A; NE3A/NE3A; NW12A/NW12A; 1A/1A; 17A/17A; 1A/1A; NE3A/NE3A; NW12A/NW12A; 5A/ 5A; NE3A/NE3A; NW12A/NW12A; 15A2/15A2
|
Crystal structures of glycoside hydrolase family 136 lacto-N-biosidases from monkey gut- and human adult gut bacteria
|
山田 千早/Chihaya YAMADA; 伏信 進矢/Shinya FUSHINOBU
|
英語 / English
|
Bioscience Biotechnology and Biochemistry
|
2022
|
86
|
464
|
| 12 | | FM14-5JB5 |
2017G149
|
5A/ 5A; 17A/17A
|
Development of a DNA aptamer that binds to the complementarity-determining region of therapeutic monoclonal antibody and affinity improvement induced by pH-change for sensitive detection
|
Taro Saito; Yutaka Shimizu; Kaori Tsukakoshi; Koichi Abe; Jinhee Lee; Kinuko Ueno; Ryutaro Asano; Brian V Jones; Tomohiro Yamada; Tatsuki Nakano; Jiaxing Tong; Asami Hishiki; Kodai Hara; Hiroshi Hashimoto; Koji Sode; Toshimasa Toyo'oka; Kenichiro Todoroki; Kazunori Ikebukuro
|
英語 / English
|
Biosensors and Bioelectronics
|
2022
|
203
|
|
| 13 | | VAMB-78D8 |
|
17A
|
Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5
|
Kimura, Izumi
|
英語 / English
|
Cell
|
2022
|
185
|
3992
|
| 14 | | RD8Z-159F |
2016G012, 2016G638, 2017G514, 2019G075, 2019G595
|
1A, 17A, NW12A
|
Varying the Directionality of Protein Catalysts for Aldol and Retro-Aldol Reactions
|
Toshifumi Fujioka
|
英語 / English
|
ChemBioChem
|
2022
|
23
|
|
| 15 | | 3GUJ-8SS8 |
2020G504
|
17A/17A
|
Activation of Positive Cooperativity by Size-Mismatch Assembly via Inclination of Guests in a Single-Site Receptor
|
松野 太輔/Taisuke MATSUNO; 高橋 奏仁/Kanato TAKAHASHI; 池本 晃喜/Koki IKEMOTO; 磯部寛之
|
英語 / English
|
Chemistry - An Asian Journal
|
2022
|
17
|
|
| 16 | | BXRB-147B |
2015G534; 2017G610; 2019G518; 2021G508; 2018G538; 2019G097; 2019G508; 2020G580; 2021G013; 2022G538
|
5A/ 5A; NW12A/NW12A; 5A/ 5A; 17A/17A; 5A/ 5A; NW12A/NW12A; 5A/ 5A; 5A/ 5A; 5A/ 5A; 5A/ 5A; 5A/ 5A; 5A/ 5A; 5A/ 5A
|
Microgravity environment grown crystal structure information based engineering of direct electron transfer type glucose dehydrogenase
|
吉田 裕美/Hiromi YOSHIDA
|
英語 / English
|
Communications Biology
|
2022
|
5
|
|
| 17 | | NXXH-MSV3 |
2020G504; 2022G596
|
17A/17A; 17A/17A
|
Target-oriented design of helical nanotube molecules for rolled incommensurate bilayers
|
磯部寛之; 小谷 祐希/Yuki KOTANI; 松野 太輔/Taisuke MATSUNO; 福永 隼也/Toshiya FUKUNAGA; 池本 晃喜/Koki IKEMOTO
|
英語 / English
|
Communications Chemistry
|
2022
|
5
|
|
| 18 | | J3JA-JCU9 |
|
17A
|
Influence of Glycan Agents on Protein Crystallization with Ammonium Sulfate
|
Guo, Yan
|
英語 / English
|
Crystal Growth & Design
|
2022
|
22
|
6751
|
| 19 | | 7PFW-FDMX |
|
17A
|
Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A
|
Miyazaki, Yuka
|
英語 / English
|
European Journal of Medicinal Chemistry
|
2022
|
227
|
|
| 20 | | EH05-4SM6 |
2018G505; 2019RP-03; 2020RP-16; 2021PF-B001
|
5A/ 5A; 17A/17A; NW12A/NW12A; 5A/ 5A; 17A/17A; 17A/17A; NW12A/NW12A; 5A/ 5A; 17A/17A
|
Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms
|
中村 亮裕/Ryosuke NAKAMURA; 藤城 貴史/Takashi FUJISHIRO
|
英語 / English
|
FEBS Journal
|
2022
|
289
|
5947
|
| 21 | | M00Z-2HYH |
|
NE3A, 17A, NW12A
|
Structural insights reveal the second base catalyst of isomaltose glucohydrolase
|
Takayoshi Tagami
|
英語 / English
|
FEBS Journal
|
2022
|
289
|
1118
|
| 22 | | 2TRF-E4TK |
2020G531
|
17A/17A
|
Crystal structures of human glyoxalase I and its complex with TLSC702 reveal inhibitor binding mode and substrate preference
|
宇佐美碧; 横山 英志/Hideshi YOKOYAMA
|
英語 / English
|
FEBS Letters
|
2022
|
596
|
1458
|
| 23 | | P5GF-SBUH |
2012G048; 2014G087; 2014R-40; 2015R-36; 2016G083; 2016R-69; 2019G017
|
17A/17A; NE3A/NE3A; NW12A/NW12A; 5A/ 5A; NE3A/NE3A; NW12A/NW12A; NW12A/NW12A; 1A/1A; NE3A/NE3A; 1A/1A; 5A/ 5A; NW12A/NW12A; 1A/1A; 17A/17A; 1A/1A; 5A/ 5A; NE3A/NE3A; NW12A/NW12A
|
Substrate complex structure, active site labeling and catalytic role of the zinc ion in cysteine glycosidase
|
丸山 瞬/Shun MARUYAMA; 澤野 孝太/Kouta SAWANO; 味木 智子/Satoko AMAKI; 荒川 孝俊/Takatoshi ARAKAWA; 山田 千早/Chihaya YAMADA; 伏信 進矢/Shinya FUSHINOBU
|
英語 / English
|
Glycobiology
|
2022
|
32
|
171
|
| 24 | | TM4R-KB4S |
|
17A
|
A conserved loop structure of GH19 chitinases assists the enzyme function from behind the core-functional region
|
Daiki Kawamoto
|
英語 / English
|
Glycobiology
|
2022
|
32
|
356
|
| 25 | | P4Y1-B889 |
2017G501
|
17A/17A; 5A/ 5A
|
Neutron crystallographic analysis of the nucleotide-binding domain of Hsp72 in complex with ADP
|
横山 武司/Takeshi YOKOYAMA
|
英語 / English
|
IUCrJ
|
2022
|
9
|
562
|
| 26 | | EHUG-42YY |
2020RP-19; 2021PF-B007
|
5A/ 5A; 17A/17A; 5A/ 5A; 17A/17A
|
Functional and Structural Insights into Human PPARα/δ/γ Subtype Selectivity of Bezafibrate, Fenofibric Acid, and Pemafibrate
|
鎌田 祥太郎/Shotaro KAMATA; 大山 拓次 / Takuji OYAMA
|
英語 / English
|
International Journal of Molecular Sciences
|
2022
|
23
|
|
| 27 | | K9AF-B537 |
2017G022
|
17A
|
Characterization and application of L-methionine γ-lyase Q349S mutant enzyme with an enhanced activity toward L-homocysteine
|
Okawa A.
|
英語 / English
|
Journal of Bioscience and Bioengineering
|
2022
|
133
|
213
|
| 28 | | PFGD-PSCJ |
2020G590
|
17A, NW12A
|
Computational and Crystallographic Analysis of Binding Structures of Inhibitory Compounds for HIV-1 RNase H Activity
|
Huiyan Lu
|
英語 / English
|
Journal of Chemical Information and Modeling
|
2022
|
62
|
6762
|
| 29 | | 083U-41KG |
2021G044
|
17A/17A
|
3CL protease inhibitors with an electrophilic arylketone moiety as anti-SARS-CoV-2 agents.
|
千田 俊哉/Toshiya SENDA
|
英語 / English
|
Journal of Medicinal Chemistry
|
2022
|
65
|
2926
|
| 30 | | JKSU-AXFW |
2017G006; 2019G016
|
17A/17A; 17A/17A
|
Chlorinated Naringenin Analogues as Potential Inhibitors of Transthyretin Amyloidogenesis
|
Mineyuki Mizuguchi
|
英語 / English
|
Journal of Medicinal Chemistry
|
2022
|
65
|
16218
|
| 31 | | XZ1X-ZSKR |
|
17A
|
Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals
|
Fukuchi, Keisuke
|
英語 / English
|
Journal of Oncology
|
2022
|
2022
|
|
| 32 | | 6AV1-XAUH |
|
17A
|
Development of a direct reading system for an RFID-tagged Uni-puck in liquid nitrogen
|
M Hirak
|
英語 / English
|
Journal of Physics: Conference Series
|
2022
|
2380
|
|
| 33 | | UGD9-79K7 |
2017G574; 2019G548; 2021G672
|
5A/ 5A; NE3A/NE3A; NW12A/NW12A; 5A/ 5A; 17A/17A; NE3A/NE3A; 5A/ 5A; NE3A/NE3A
|
Molecular Basis for Enzymatic Aziridine Formation via Sulfate Elimination
|
黒澤 菫/Sumire KUROSAWA; 吉田 彩子/Ayako YOSHIDA; 富田 武郎/Takeo TOMITA; 古園 さおり/Saori KOSONO; 西山 真/Makoto NISHIYAMA
|
英語 / English
|
Journal of the American Chemical Society
|
2022
|
144
|
16164
|
| 34 | | AE9B-0NK3 |
|
17A
|
Crystal Structures of the Plant Phospholipase A1 Proteins Reveal a Unique Dimerization Domain
|
Heo Y.
|
英語 / English
|
Macromolecules
|
2022
|
27
|
2317
|
| 35 | | G7UT-YZCY |
2019G539
|
17A/17A
|
The effect of inosine on the spectroscopic properties and crystal structure of a NIR-emitting DNA-stabilized silver nanocluster
|
Cecilia Cerretani; Mikkel B. Liisberg; Vanessa R?ck; 近藤 次郎/Jiro KONDO; Tom Vosch
|
英語 / English
|
Nanoscale Advances
|
2022
|
4
|
3212
|
| 36 | | XJHC-HEEY |
2017G127; 2019G008; 2021G041
|
17A/17A; 17A/17A; 17A/17A
|
Reversible RNA phosphorylation stabilizes tRNA for cellular thermotolerance.
|
富田 耕造/Kozo TOMITA; 山下 征輔/Seisuke YAMASHITA; 蓑輪 恵一/Keiichi MINOWA; 大平 高之/TAKAYUKI OHIRA
|
英語 / English
|
Nature
|
2022
|
605
|
372
|
| 37 | | XKP6-93ME |
|
17A
|
Exploration and structure-based engineering of alkenal double bond reductases catalyzing the Cαsingle bondCβ double bond reduction of coniferaldehyde
|
Naofumi Kamimura
|
英語 / English
|
New Biotechnology
|
2022
|
68
|
57
|
| 38 | | GKE9-5319 |
2019G008; 2021G041
|
17A/17A; 17A/17A
|
Mechanistic insights into tRNA cleavage by a contact-dependent growth inhibitor protein and translation factors
|
富田 耕造/Kozo TOMITA; 八代 悠歌/Yuka YASHIRO; 王 晶/Jing WANG
|
英語 / English
|
Nucleic Acids Research
|
2022
|
50
|
4713
|
| 39 | | 80MP-TFAX |
|
NE3A, 5A, 17A
|
Structural basis of transcription regulation by CNC family transcription factor, Nrf2
|
Sengoku, Toru
|
英語 / English
|
Nucleic Acids Research
|
2022
|
50
|
12543
|
| 40 | | VGM0-DZT1 |
2018G621
|
17A
|
Structure, mechanism, and phylogeny of LysM-chitinase conjugates specifically found in fern plants
|
Kitaoku, Yoshihito
|
英語 / English
|
Plant Science
|
2022
|
321
|
|
| 41 | | 5Z5B-JBVW |
2017G167; 2019G027; 2021G031
|
5A/ 5A; NW12A/NW12A; NE3A/NE3A; 17A/17A
|
Visualization of mutagenic nucleotide processing by Escherichia coli MutT, a Nudix hydrolase
|
中村 照也/Teruya NAKAMURA; 山縣 ゆり子/Yuriko YAMAGATA
|
英語 / English
|
Proceedings of the National Academy of Sciences of the United States of America
|
2022
|
119
|
|
| 42 | | PZKD-MH3F |
2016G048; 2016R-19
|
17A/17A; 1A/1A
|
Discovery of ultrafast myosin, its amino acid sequence, and structural features
|
Takeshi Haraguchi; Masanori Tamanaha; 鈴木 花野/Kano SUZUKI; Kohei Yoshimura; Takuma Imi; Motoki Tominaga; Hidetoshi Sakayama; Tomoaki Nishiyama; 村田 武士/Takeshi MURATA; Kohji Ito
|
英語 / English
|
Proceedings of the National Academy of Sciences of the United States of America
|
2022
|
119
|
|
| 43 | | 7DF3-YVBF |
|
17A
|
Crystal structure of the Ate1 arginyl-tRNA-protein transferase and arginylation of N-degron substrates
|
Kim B. H.
|
英語 / English
|
Proceedings of the National Academy of Sciences of the United States of America
|
2022
|
119
|
|
| 44 | | 80HA-Z7W9 |
2019G024
|
17A
|
CRY2 isoform selectivity of a circadian clock modulator with antiglioblastoma efficacy
|
Miller, Simon
|
英語 / English
|
Proceedings of the National Academy of Sciences of the United States of America
|
2022
|
119
|
|
| 45 | | TCNW-5CR3 |
2013G526; 2015G517
|
17A/17A; 17A/17A
|
Hybrid in vitro/in silico analysis of low-affinity protein-protein interactions that regulate signal transduction by Sema6D
|
禾 晃和/Terukazu NOGI; 田中 翼/Tsubasa TANAKA
|
英語 / English
|
Protein Science
|
2022
|
31
|
e4452
|
| 46 | | URN0-J97N |
2014G517
|
17A/17A
|
Structural basis for peptide recognition by archaeal oligopeptide permease A
|
横山 英志/Hideshi YOKOYAMA
|
英語 / English
|
Proteins-Structure Function and Bioinformatics
|
2022
|
90
|
1434
|
| 47 | | TWPH-CSP4 |
2017G518; 2019G510
|
17A/17A; 1A/1A; 17A/17A; 1A/1A
|
Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP
|
禾 晃和/Terukazu NOGI; 高貫 一徳/Kazunori TAKANUKI; 三好 賢一/Kenichi MIYOSHI; 有賀 理江/Rie ARUGA
|
英語 / English
|
Science Advances
|
2022
|
8
|
|
| 48 | | WZ17-K2TW |
|
17A
|
A unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin
|
Miho Watanabe-Takahashi
|
英語 / English
|
Scientific Reports
|
2022
|
12
|
|
| 49 | | 2DZJ-2Z76 |
2019G063; 2021G054
|
17A/17A; 1A/1A; 17A/17A
|
The GTP responsiveness of PI5P4Kβ evolved from a compromised trade-off between activity and specificity
|
竹内 恒/Koh TAKEUCHI; MIki Sennda; Lisa Nagase; Toshiya Senda
|
英語 / English
|
Structure
|
2022
|
30
|
886
|
| 50 | | FVB3-JA1R |
2020G504
|
17A/17A
|
A large-bore chiral cylindrical molecule prone to radial deformations
|
尾仲 柚香/Yuzuka ONAKA; 田中舜; 小林綾乃; 松野 太輔/Taisuke MATSUNO; 磯部寛之
|
英語 / English
|
Tetrahedron Letters
|
2022
|
96
|
153774
|
